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Synthesis and antimicrobial activity of some novel furyl and benzimidazole substituted benzyl ethers

✍ Scribed by Özden Özel Güven; Taner Erdoǧan; Hakan Göker; Sulhiye Y1ld1z

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
298 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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In this study, a series of novel furyl and benzimidazole substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against S. aureus, Methicillin resistant S. aureus (MRSA), E. coli, C. albicans and C. krusei. Compound 6f and 6h exhibited the most potent anti‐bacterial activity with lowest MIC values of 3.12 μg/mL against S aureus and MRSA, respectively.

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Synthesis and Antimicrobial Activity of Some New Anilino Benzimidazoles. -A series of new anilinobenzimidazoles such as (III), (V), (VI), and (IX) are prepared and evaluated for their in vitro antibacterial and antifungal activity. Compound (IIIb), (IXa) and (IXb) exhibit the best activity.