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Synthesis and antimicrobial activity of some new 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones

✍ Scribed by Seçkin Özden; Aydin Murat Öztürk; Hakan Göker; Nurten Altanlar

Book ID: 114018858
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 67 KB
Volume: 55
Category: Article
ISSN: 0014-827X
DOI: 10.1016/s0014-827x(00)00098-7

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## Abstract Substituted 2‐(benzylamino)‐2__H__‐1,4‐benzoxazin‐3(4__H__)‐ones are unstable under alkaline and acidic conditions, undergoing opening of the benzoxazinone ring. 2‐Bromo‐2__H__‐1,4‐benzoxazin‐3(4__H__)‐ones show similar degradation under alkaline conditions, while replacement of Br at C