## Abstract Novel metronidazoleβsubstituted 1,2,4βtriazoleβ3βthiole derivatives (III) and (IV) respectively are prepared and tested for their antiparasitic, cytotoxic, antibacterial, and antifungal activity.
Synthesis and antimicrobial activity of new 1,2,4-triazole-3-thiol metronidazole derivatives
β Scribed by Haythem A. Saadeh; Ibrahim M. Mosleh; Amal G. Al-Bakri; Mohammad S. Mubarak
- Publisher
- Springer Vienna
- Year
- 2010
- Tongue
- English
- Weight
- 260 KB
- Volume
- 141
- Category
- Article
- ISSN
- 0026-9247
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## By means of regioselective S-alkylation of 1H-1,2,4-triazole-3-thiol (1), a series of S-substituted derivatives 2a-j were synthesized. In certain conditions, the reaction of 2 with arylsulfochlorides, arylisocyanates, and quaternary ammonium salts of azines corresponding compounds were obtained