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Synthesis and antimicrobial activity of 2,6-dimethyl-3,5-dialkoxycarbonyl-4-phenyl- 1,4-dihydropyridines

✍ Scribed by V. L. Gein; M. I. Kazantseva; A. A. Kurbatova; E. V. Voronina


Publisher
Springer
Year
2011
Tongue
English
Weight
69 KB
Volume
45
Category
Article
ISSN
0091-150X

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Synthesis of 3,5-diacyl-4-phenyl-1,4-dih
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3,5-Diacyl-4-phenyl-l,4-dihydropyridines have been synthesized via a regio-and chemoselective addition of Ph2Cu(CN)Li2 to I~-substituted N-alkylpyridinium salts, followed by acylation of the intermediate 1,4dihydropyridines with trichloroacetic anhydride and subsequent haloform-type reaction. A simi