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Synthesis and antihypertensive activity of indolin-2-one dienediamines

✍ Scribed by I. P. Graevsksya; S. Yu. Ryabova; L. M. Alekseeva; M. A. Kalinkina; M. É. Kaminka; V. G. Granik

Book ID
105586503
Publisher
Springer
Year
1998
Tongue
English
Weight
300 KB
Volume
32
Category
Article
ISSN
0091-150X

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Rapid synthesis and bioactivities of 3-(nitromethylene)indolin-2-one analogues
✍ Gang Chen; Xiao-Jiang Hao; Qian-Yun Sun; Jian Ding 📂 Article 📅 2010 🏛 Versita 🌐 English ⚖ 210 KB

## Abstract A new synthesis method of 3-(nitromethylene)indolin-2-one analogues is described, using the Henry reaction of isatin and N-substituted isatins with nitromethane followed by dehydration of the nitroaldol adduct with mesyl chloride. The use of diethylamine (rather than DBU) as the base ca