✍ Scribed by Monika Gupta
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5‐Aryl‐3,4‐diamino‐1,2,4‐triazoles 5 on treatment with β‐chlorocinnamaldehydes 7 in the presence of catalytic amount of p‐TsOH and N,N‐dimethylformamide as an energy transfer medium under microwave irradiation and as solvent with oil‐bath heating at 80 °C affords novel 3,6‐diaryl‐5__H__‐[1,2,4]triazolo[4,3‐b]‐1,2,4]triazepines 8. The structures of the synthesized compounds were established on the basis of ^1^H NMR, IR, mass spectral data and elemental analysis.
📜 SIMILAR VOLUMES
## Abstract A simple, efficient and environmentally friendly procedure for the synthesis of title compounds (III) (10 examples) is developed.
## Abstract The reaction of N‐aryl‐C‐ethoxycarbonyl nitrilimines with [1,2,4]triazepin‐3,5‐dithione leads to title compounds. The 1,3‐dipolar cycloaddition is completely peri and regioselective. The preferred orientation of addition is predicted correctly by AM~1~ calculation.