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Synthesis and Antifungal Activity of Novel 14-Membered Benzomacrolides as Galbonolide Analogues.

✍ Scribed by Hiroki Sakoh; Shunji Sakuraba; Yuichi Sugimoto; Hideaki Imamura; Hideki Jona; Koji Yamada; Rie Bamba-Nagano; Terutaka Hashizume; Hajime Morishima


Publisher
John Wiley and Sons
Year
2004
Weight
273 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract In a study aiming to determine the structural elements essential to the antifungal activity of kakuol, we synthesized a series of 2‐hydroxy‐4,5‐methylenedioxyaryl ketones, and we assayed their __in vitro__ antifungal activity. The most sensitive target organisms to the action of these c