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Synthesis and Antifungal Activity of 3′-Deoxyribonucleosides

✍ Scribed by Kumar, Anil; Khan, Shoeb I.; Manglani, Anita; Khan, Z. K.; Katti, S. B.

Book ID
120478086
Publisher
Taylor and Francis Group
Year
1994
Tongue
English
Weight
371 KB
Volume
13
Category
Article
ISSN
0732-8311

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Synthesis and Antifungal Activity of 3-Deoxy-DL-prumycin Analogues
✍ Constantinou-Kokotou, Violetta ;Kokotos, George ;Chrysayi-Tokousbalides, Maria ; 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 373 KB

## Abstract A number of 3‐deoxy‐DL‐prumycin analogues containing one or more amino acid moieties were synthesized. Key intermediate 2 afforded ester analogues by coupling with H‐D‐ or L‐Ala‐OH, while intermediates 6 and 9 afforded amide analogues by coupling with H‐D‐Ala‐D‐Ala‐OH, H‐D‐Ala‐OH, 2‐ami