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Synthesis and antifungal activity against strains of candida albicans of 6-fluoro-4(5 or 7)-chloro-2-(difluorobenzoyl)aminobenzothiazoles

✍ Scribed by Domenico Armenise; Nicolino De Laurentis; Antonia Reho; Antonio Rosato; Flaviano Morlacchi

Publisher: Journal of Heterocyclic Chemistry
Year: 2004
Tongue: English
Weight: 147 KB
Volume: 41
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570410520

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✦ Synopsis

Abstract

A series of 6‐fluoro‐4‐(5 or 7)‐chloro‐2‐(difluorobenzoyl)aminobenzothiazoles 3a‐r were prepared to investigate their potential biological activity. In this work, the results of their in vitro antifungal activity against some strains of Candida albicans are reported. It was found that some derivatives displayed antifungal activity higher than that for 3k [1a] compound already described in literature.

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