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Synthesis and Antidepressant and Anxiolytic Activity of 1,2,4,5-Tetrahydro-3H-Pyrrolo[1,2-a][1,4]Diazepin-3-ones

✍ Scribed by G. V. Mokrov,A. M. Likhosherstov,V. I. Poseva…

Book ID: 121481247
Publisher: Springer
Year: 2013
Tongue: English
Weight: 106 KB
Volume: 47
Category: Article
ISSN: 0091-150X
DOI: 10.1007/s11094-013-0981-7

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## Abstract Fused tricyclic 7‐phenyl‐5__H__‐thizolo[5,4‐__e__]pyrrolo[1,2‐__a__][1,4]diazepin‐10(9__H__)one (**10**) was prepared by thermolysis of 2‐phenyl‐4‐(1‐pyrrolylmethyl)thiazole‐5‐carbonyl azide (**9**) in acetic acid. In addition, starting from **10**, 7‐phenyl‐5__H__‐thiazolo [5,4‐__e__][