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Synthesis and anticonvulsant activity of substituted tetrahydropyran amides and amines

✍ Scribed by N. S. Arutyunyan; L. A. Akopyan; R. G. Paronikyan; N. E. Akopyan


Book ID
112401308
Publisher
Springer
Year
1990
Tongue
English
Weight
338 KB
Volume
24
Category
Article
ISSN
0091-150X

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## Abstract A series novel of __N__‐(2‐hydroxyethyl)amide derivatives was synthesized and screened for their anticonvulsant activities by the maximal electroshock (MES) test, and their neurotoxicity was evaluated by the rotarod test (Tox). The maximal electroshock test showed that __N__‐(2‐hydroxye