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Synthesis and Anticonvulsant Activity of New Dibenzo[1,2]thiazepine S,S-Dioxides

โœ Scribed by Juan A. Diaz; Enrique Montero; Salvador Vega; Victoriano Darias; M. Luisa Tello; Suzanne S. Abdallah

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
390 KB
Volume
327
Category
Article
ISSN
0365-6233

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โœ Ching-Hsin Kung; John N.D. Wurpel; Chul-Hoon Kwon ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 130 KB ๐Ÿ‘ 2 views

A series of (S)-(+)-5-n-propyl-2-iminohydantoins with various N-1 substituents were synthesized and tested for anticonvulsant activity to better understand the structure-activity relationship (SAR) of 2-iminohydantoins. Compounds with N-1 phenoxycarbonyl (2), ethoxycarbonyl (6), t-butoxycarbonyl (7)