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Synthesis and anticancer effects of pongamol derivatives on mitogen signaling and cell cycle kinases

โœ Scribed by R. Ranga Rao; Vishal Chaturvedi; K. Suresh Babu; P. Prabhakar Reddy; V. Rama Subba Rao; P. Sreekanth; A. S. Sreedhar; J. Madhusudana Rao


Book ID
113015036
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
423 KB
Volume
21
Category
Article
ISSN
1054-2523

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โœ Patrick L. Crittenden; Nikolay M. Filipov ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 712 KB

Multiple studies demonstrate that manganese (Mn) exposure potentiates inflammatory mediator output from activated glia; this increased output is associated with enhanced mitogen activated protein kinase (MAPK: p38, ERK and JNK) activity. We hypothesized that Mn activates MAPK by activating the kinas