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Synthesis and antiarrhythmic activity of substituted 3-p-chlorophenoxy-acetylaminoquinuclidines

โœ Scribed by O. R. Arbuzova; K. A. Zaitseva; E. E. Mikhlina; L. N. Yakhontov


Book ID
112400629
Publisher
Springer
Year
1984
Tongue
English
Weight
270 KB
Volume
18
Category
Article
ISSN
0091-150X

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Antiarrhythmic activity of 3-amino-3-met
โœ M. J. Kornet; P. A. Thio; N. Malone; W. C. Lubawy ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 409 KB

A series of 3-amino-3-methyloxindoles was synthesized from indoles by modification of previously described procedures. All compounds showed activity against chloroform-induced arrhythmias in mice. One member of the series, 3-methyl-3-piperidinooxindole, displayed activity equal to that of lidocaine