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Synthesis and anti-staphylococcal activity of new halogenated pyrroles related to Pyrrolomycins F

✍ Scribed by Maria Valeria Raimondi; Domenico Schillaci; Salvatore Petruso

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
325 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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The chemical synthesis of new halogenated pyrroles related to pyrrolomycins F is described and the anti‐staphylococcal activity compared. The replacement of 4′‐bromo atom of parent compounds with two chloro atoms at 3β€² and 5β€² position increase the antibacterial activity against a reference strain of S. aureus.

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