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Synthesis and anti-Influenza virus activity of 7-O-Alkylated derivatives related to zanamivir

✍ Scribed by Takeshi Honda; Takeshi Masuda; Shuku Yoshida; Masami Arai; Satoru Kaneko; Makoto Yamashita


Book ID
108477243
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
149 KB
Volume
12
Category
Article
ISSN
0960-894X

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## Abstract Varied positioning of the hydroximino group on the parental steroid skeleton results in remarkable changes in the antineoplastic activity profile of the compounds. Here, the compound 7‐oximino‐5‐androstene and its __O__‐alkylated derivatives have been prepared and screened for cytotoxic