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Synthesis and anti-inflammatory evaluation of some pyrazolo[3,4-b]pyridines

✍ Scribed by Pawan K. Sharma; Karan Singh; Surender Kumar; Pawan Kumar; S. N. Dhawan; Sukhbir Lal; Holger Ulbrich; Gerd Dannhardt


Book ID
105771073
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
298 KB
Volume
20
Category
Article
ISSN
1054-2523

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Synthesis of some new bipyridines, thien
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## Abstract Cyclocondensation of cyanoacetamide and cyanothioacetamide with sodium salt of 3‐hydroxy‐1‐(pyridin‐3‐yl)prop‐2‐en‐1‐one gave 6‐oxo‐[2,3β€²]bipyridine **5a** and 6‐thioxo‐[2,3β€²]bipyridine **5b** derivatives, respectively. Compound **5b** upon treatment with different methylenes **8** gave