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Synthesis and anti-inflammatory and analgesic activities of pyridyloxy- and phenoxyalkanoic acid derivatives

โœ Scribed by Kuk Hyun Shin; Soon Sung Lim; Sang Hoon Jung; Jun Ji; Eun Bang Lee; Dong Chan Kim; Kye Jung Shin; Dong Jin Kim; Sang Woo Park

Publisher
Springer
Year
2000
Tongue
English
Weight
296 KB
Volume
23
Category
Article
ISSN
0253-6269

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โœ Hamdy M. Abdel-Rahman; Mostafa A. Hussein ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 614 KB

## Abstract A series of new 3โ€(substituted) 3โ€hydroxyโ€propanoic acid ethyl esters **1aโ€“c**, hydrazides **2aโ€“c**, thiosemicarbazides **3aโ€“f**, and semicarbazides **3g**, **3h** has been synthesized. Cyclization of compounds **3aโ€“d** in basic medium yielded 1,2,4โ€triazoleโ€5โ€thiones **4aโ€“d**. On the o