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Synthesis and Anti-inflammatory Activity of N-(4, 6-Dimethylpyridin-2-yl) β-Ketoamides and Derivatives

✍ Scribed by S. ROBERT-PIESSARD; O. DUVAL; D. SERAPHIN; J. M. ROBERT; M. R. NOURRISSON; G. LE BAUT; N. GRIMAUD


Book ID
118110381
Publisher
Pharmaceutical Press
Year
1997
Tongue
English
Weight
357 KB
Volume
3
Category
Article
ISSN
2042-7158

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Synthesis and anti-inflammatory activity
✍ Santosh N. Mokale; Sandeep S. Shinde; Rupali D. Elgire; Jaiprakash N. Sangshetti 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 751 KB

A series of 3-(4,6-disubtituted-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl) propanoic acid derivatives has been synthesized by condensation of thiourea, 5-(4-subtituted phenyl)-5-oxopentanoic acid and substituted aldehyde. The synthesized compounds were screened for their anti-inflammatory activity u