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Synthesis and anti-inflammatory activity of 3,1-benzoxazin-4(3H)-ones andN-acyl-5-iodoanthranilic acid amides

✍ Scribed by E. R. Kurbatov; A. V. Kurochkin; L. M. Korkodinova; B. Ya. Syropyatov; L. N. Markova

Publisher
Springer
Year
2008
Tongue
English
Weight
64 KB
Volume
42
Category
Article
ISSN
0091-150X

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Substituted 3-hydroxyquinoline-2,4(1H,3H )-diones 3 were transformed into 3-acyloxy-1,3-dihydro-2H-indol-2-ones 4 and isomeric 4-acyl-1,4-dihydro-3,1-benzoxazin-2-ones 5. The influence of the substituents and the reaction conditions on the course of the reaction was studied. In the proposed mechanis