𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Anti-HIV Activity of 4′-Substituted 4′-Thiothymidines: A New Entry Based on Nucleophilic Substitution of the 4′-Acetoxy Group

✍ Scribed by Haraguchi, Kazuhiro; Shimada, Hisashi; Tanaka, Hiromichi; Hamasaki, Takayuki; Baba, Masanori; Gullen, Elizabeth A.; Dutschman, Ginger E.; Cheng, Yung-Chi


Book ID
120444977
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
188 KB
Volume
51
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Nucleophilic Substitution of 4H-Imidazol
✍ Jens Atzrodt; Rainer Beckert; Wolfgang Günther; Helmar Görls 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 295 KB 👁 2 views

The electrophilic properties of the 4H-imidazoles 1 and their protonated derivatives 2 permit the introduction of nucleophilic building blocks, as illustrated by reactions of 1 with selected amines. Depending on the nature of the amine and the substituents R 1 on the heterocycle 1, single (3) or dou