✦ LIBER ✦

Synthesis and anti-HCV activity of a new 2′-deoxy-2′-fluoro-2′-C-methyl nucleoside analogue

✍ Scribed by Weidong Hu; Ping’an Wang; Chuanjun Song; Zhenliang Pan; Qiang Wang; Xiaohe Guo; Xuejun Yu; Zhenhua Shen; Shuyang Wang; Junbiao Chang

Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 260 KB
Volume: 20
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2010.10.076

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✦ Synopsis

2 0 -Deoxy-2 0 -fluoro-2 0 -C-methyl nucleoside Anti-HCV activity a b s t r a c t 2 0 -Deoxy-2 0 -fluoro-2 0 -C-methyl nucleoside analogue 4 was designed and synthesized. Initial biological studies indicated that this compound showed promising activity against HCV replication.

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