Synthesis and anti-HBV activity of 2′-fluoro-β-l-arabinofuranosyl purine nucleosides
✍ Scribed by T. Ma; J.-S. Lin; Y.-C. Cheng; C.K. Chu
- Book ID
- 114145032
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 104 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0166-3542
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The synthesis of 9-(2,3.dideoxy-2.fluoro-L.glycero.pent-2-eno-furanosyl)adenine and d~ypoxanthine has been accomplished by direct condensation of silylated 6-chloropurine with key intermediates 8, which were prepared starting from 2,3-O-isopropylidene-L-glyceraldehyde. The synthesized nucleosides we
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