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Synthesis and analgesic activity of pemedolac [cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indole-1-acetic acid]

✍ Scribed by Katz, Alan H.; Demerson, Christopher A.; Shaw, Chia Cheng; Asselin, Andre A.; Humber, Leslie G.; Conway, Kimberly M.; Gavin, Gregory; Guinosso, Charles; Jensen, Norman P.


Book ID
115524578
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
1002 KB
Volume
31
Category
Article
ISSN
0022-2623

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Eingegangen am 31. Oktober 1986 Pyrano[ 3,4-blindolones 3a-d are available from a-ethoxyalyllactones la, c and disubstituted hydrazines 2a, b without isolation of intermediates. In a two-phase system, however, the intermediate hydrazones 4a, c can be isolated. Conversion of 3a-d into P-carbolines wa