Design and syntheses of methyl 2-methyl-
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Sammy Agudoawu; Huiying Li; Amgad G. Habeeb; P.N. Praveen Rao; Mavanur R. Suresh
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Article
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2000
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John Wiley and Sons
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English
โ 194 KB
A group of methyl 2-methyl-2- [2-(4-benzoyl-5-phenyl-7-halo-2-azabicyclo[4.1.0]hept-3ene)]acetates (1015), and the related acetamide derivative ( 16), that possess a variety of C-7 substituents (Br, Cl, F, H), were designed for evaluation as analgesic-antiinflammatory agents. The effect of the C-7 s