Synthesis and Agonistic Activity at the GPR35 of 5,6-Dihydroxyindole-2-carboxylic Acid Analogues
β Scribed by Deng, Huayun; Fang, Ye
- Book ID
- 127396244
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 656 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1948-5875
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π SIMILAR VOLUMES
In a recent work addressing the structural characterization of melanin pigments, we reported the isolation and characterization of trimeric oligomers of 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a key intermediate in the biosynthesis of the dark brown eumelanins, by tyrosine catalyzed oxidation
Matrix-assisted laser desorptionhonization mass spectrometry was applied to the structural investigation of synthetic melanins prepared by enzymatic or chemical oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a major biosynthetic precursor. Following optimization of the experimental cond