Synthesis of enzymatically resistant noc
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Melinda Ligeti; Szilvia BΓΆsze; Antal CsΓmpai; Γzge GΓΌndΓz; Mahmud Al-khrasani; A
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Article
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2006
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John Wiley and Sons
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English
β 173 KB
## Abstract Nociceptin, a 17βamino acid peptide (FGGFTGARKSARKLANQ, N/OFQ), is the endogenous ligand of the nociceptin/orphanin FQ (NOP) receptor. This receptorβligand system is involved in various physiological as well as pathophysiological mechanisms, but owing to the peptidic structure, it is ra