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Synthesis and absolute configuration of the first optically active organic molecule with T symmetry: (-)-1,3,5,7-tetrakis[[(2-(1S,3S,5R,6S,8R,10R)-D3-trishomocubanyl)acetoxy]methyl]adamantane

✍ Scribed by Nakazaki, Masao; Naemura, Koichiro


Book ID
120401861
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
788 KB
Volume
46
Category
Article
ISSN
0022-3263

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Preparation via Diastereoselective Hydro
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Hydrogenation of the ketone group in di-0-benzylderivative (8) of the known macrocyclic lactone zeralenone (7) using a novel chiral borane complex 3.BH3, prepared in situ, proceeded at lower temperatures with moderate diastereoselectivity ( -40%, d.e. at -60"). Unsaturated diastereomers 9 and 10 wer

ChemInform Abstract: Synthesis of (+)-(1