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Synthesis, absolute configuration and conformation of the aldose reductase inhibitor sorbinil

✍ Scribed by Sarges, Reinhard; Bordner, Jon; Dominy, Beryl W.; Peterson, Michael J.; Whipple, Earl B.

Book ID
125995221
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
558 KB
Volume
28
Category
Article
ISSN
0022-2623

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Clinical and neurophysiological studies
Clinical and neurophysiological studies with the aldose reductase inhibitor, sorbinil, in symptomatic diabetic neuropathy
✍ I. G. Lewin; I. A. D. O'Brien; M. H. Morgan; R. J. M. Corrall πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 436 KB

The effect of sorbinil (200 mg daily for 4 weeks) was examined in 13 patients, mean age 59.7 years (range 42-72 years), with symptomatic diabetic neuropathy of mean duration 6 year (range 1-18 years). In this double-blind, placebo-controlled crossover trial, studies were made of motor, sensory and a