Syntheses of Tetrahydrolipstatin and Absolute Configuration of Tetrahydrolipstatin and Lipstatin
β Scribed by Pierre Barbier; Fernand Schneider
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- German
- Weight
- 426 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0018-019X
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π SIMILAR VOLUMES
Tetrahydrolipstatin (1) and its analogue 2 are representatives of a new class of pancreatic-lipase inhibitors. Two stereoselective synthetic approaches are described. Early syntheses of tetrahydrolipstatin (l), in connection with the determination of its absolute configuration, have already been de
## Abstract Stereospecific syntheses of (__E__)β and (__Z__)βΞ±βbisabolenes have made revision of the configuration of natural (+)βΞ±βbisabolene from __Opoponax__ oil necessary. ^13^CβNMR. spectroscopy has been used for the differentiation of these isomers.