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Syntheses of Tetrahydrolipstatin and Absolute Configuration of Tetrahydrolipstatin and Lipstatin

✍ Scribed by Pierre Barbier; Fernand Schneider


Publisher
John Wiley and Sons
Year
1987
Tongue
German
Weight
426 KB
Volume
70
Category
Article
ISSN
0018-019X

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πŸ“œ SIMILAR VOLUMES


Stereoselective Syntheses of Tetrahydrol
✍ Pierre Barbier; Fernand Schmeider; Ulrich Widmer πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 German βš– 529 KB

Tetrahydrolipstatin (1) and its analogue 2 are representatives of a new class of pancreatic-lipase inhibitors. Two stereoselective synthetic approaches are described. Early syntheses of tetrahydrolipstatin (l), in connection with the determination of its absolute configuration, have already been de

Syntheses and Absolute Configuration of
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## Abstract Stereospecific syntheses of (__E__)‐ and (__Z__)‐α‐bisabolenes have made revision of the configuration of natural (+)‐α‐bisabolene from __Opoponax__ oil necessary. ^13^C‐NMR. spectroscopy has been used for the differentiation of these isomers.