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Syntheses of substituted 2-(2-alkylthio-1-benzyl-5-imidazolyl)-1,3,4-oxadiazoles

โœ Scribed by F. Hadizadeh; F. I. Tafti

Publisher
Journal of Heterocyclic Chemistry
Year
2002
Tongue
English
Weight
31 KB
Volume
39
Category
Article
ISSN
0022-152X

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โœฆ Synopsis

Abstract

Starting from the readily available benzylamine hydrochloride a series of 2โ€(2โ€alkylthioโ€1โ€benzylโ€5imidaโ€zolyl)โ€1,3,4โ€oxadiazoles were prepared.

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## Abstract Arylation of the readily available 3โ€alkythioโ€5โ€arylโ€1,2,4โ€triazoles gave 5โ€alkylthioโ€1,3โ€diarylโ€1,2,4โ€triazoles in moderate yield. The structures of the latter were confirmed by NOE and ^13^Cโ€NMR.