✦ LIBER ✦

Syntheses of (S)-5-substituted 4-aminopentanoic acids: a new class of .gamma.-aminobutyric acid transaminase inactivators

✍ Scribed by Silverman, Richard B.; Levy, Mark A.

Book ID: 121432405
Publisher: American Chemical Society
Year: 1980
Tongue: English
Weight: 586 KB
Volume: 45
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo01293a011

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A New Class of Conformationally Rigid An

A New Class of Conformationally Rigid Analogues of 4-Amino-5-halopentanoic Acids, Potent Inactivators of γ-Aminobutyric Acid Aminotransferase

✍ Qiu, Jian; Silverman, Richard B. 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 489 KB

ChemInform Abstract: A New Class of Conf

ChemInform Abstract: A New Class of Conformationally Rigid Analogues of 4-Amino-5-halopentanoic Acids, Potent Inactivators of γ-Aminobutyric Acid Aminotransferase.

✍ Jian Qiu; Richard B. Silverman 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

In vitro and in vivo effects on brain GA

In vitro and in vivo effects on brain GABA metabolism of (S)-4-amino-5-fluoropentanoic acid, a mechanism-based inactivator of γ-aminobutyric acid transaminase

✍ Richard B. Silverman; A. Jabbar Muztar; Mark A. Levy; James D. Hirsch 📂 Article 📅 1983 🏛 Elsevier Science 🌐 English ⚖ 396 KB

Mechanism of inactivation of .gamma.-ami

Mechanism of inactivation of .gamma.-aminobutyrate aminotransferase by 4-amino-5-fluoropentanoic acid. First example of an enamine mechanism for a .gamma.-amino acid with a partition ratio of 0

✍ Silverman, Richard B.; Invergo, Benedict J. 📂 Article 📅 1986 🏛 American Chemical Society 🌐 English ⚖ 444 KB

Inactivation of .gamma.-aminobutyric aci

Inactivation of .gamma.-aminobutyric acid aminotransferase by (S,E)-4-amino-5-fluoropent-2-enoic acid and effect on the enzyme of (E)-3-(1-aminocyclopropyl)-2-propenoic acid

✍ Silverman, Richard B.; Invergo, Benedict J.; Mathew, Jacob 📂 Article 📅 1986 🏛 American Chemical Society 🌐 English ⚖ 971 KB

Enantiospecific synthesis of (s)-4-amino

Enantiospecific synthesis of (s)-4-amino-4,5-dihydro-2-furancarboxylic acid, a new suicide inhibitor of gaba-transaminase.

✍ Joseph P. Burkhart; Gene W. Holbert; Brian W. Metcalf 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 184 KB

The title compound has been prepared in optically pure form from (S)-glutamic acid.