The title trisaccharide glycosides were needed for studies of the interactions of &tins, receptor sites for bacteriophages with Salmonella lipopolysaccharide corespecificity, and correlation of n.m.r. chemical shifts and structure. The methods used in the syntheses were conventional. Thus, 2,3,4,6-
Syntheses of model oligosaccharides of biological significance.Synthesis of methyl 3,6-DI-O-(α-d-mannopyranosyl)-α-d-mannopyranoside and the corresponding mannobiosides
✍ Scribed by Françoise M. Winnik; Jean-Robert Brisson; Jeremy P. Carver; Jiri J. Krepinsky
- Book ID
- 108309610
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 762 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0008-6215
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📜 SIMILAR VOLUMES
The t i t l e trisaccharide has been synthesized containing a 3-deuterated central mannopyranosyl unit and 2,3,4,6,6'-pentadeuterio mannopyranosyl units i n both arms. 2-Propyl 2-0-benzyl-4,6-0-benzylidene-3-deuterlo- -I)-D-mannopyranoside was obtained by stereoselective deuteride reduction of the c
Reaction of p-trifluoroacetamidophenyl2,4-di-O-benzyl-a-r>-mannopyranoside with 2-0-acetyl-3,4,6-tri-O-benzyl-cy-D-mannopyranosyl chloride gave a trisaccharide derivative which was 0-deacetylated and then treated with ethyl 2,3,4tri-O-benzyl-6-O-dibenzyloxyphosphoryl-l-thio-a-D-mannopyIanoside. The
All of the monodeoxy analogues of methyl 3,6-di-O-alpha-D-mannopyranosyl-alpha-D-mannopyranoside have been synthesized together with two dideoxy (2,3'- and 4,3'-) analogues. The 2'- and 2"-deoxy functions were introduced by NIS-promoted couplings with 2,3,4-tri-O-acetyl-D-glucal as donor, followed b