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Syntheses of homologous, tritium-labelled photoaffinity analogs of the natural juvenile hormones JH I, JH II, and JH III

✍ Scribed by István Ujváry; Wai-Si Eng; Glenn D. Prestwich


Publisher
John Wiley and Sons
Year
1990
Tongue
French
Weight
363 KB
Volume
28
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

Enantiomerically enriched (≥92% e.e.) tritium‐labelled diazoacetate photoaffinity analogs EBDA and EHDA (each 58 Ci/mmol) and EFDA (14 Ci/mmol) were prepared from the corresponding tritiated juvenile hormone (JH) homologs JH I, JH II, and JH III in two steps. Selective reduction of the ester group and subsequent acylation gave the target compounds.