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Syntheses of cyclotetradepsipeptides, am-toxin I and its analogs

✍ Scribed by Sannamu Lee; Haruhiko Aoyagi; Yasuyuki Shimohigashi; Nobuo Izumiya; Tamio Ueno; Hiroshi Fukami

Publisher
Elsevier Science
Year
1976
Tongue
French
Weight
253 KB
Volume
17
Category
Article
ISSN
0040-4039

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✦ Synopsis

For the synthesis of a cyclotetradepslpeptlde correspondlng to the sequence of AM-Torln I C&j, [O-Me-L-Tyrll-AM-Toxin (l&j was selected as a model peptlde in a prellmlnary siudy Synthesis of &was attempted through SIX different routes, and one (the route D) afforded the lb in a good yield Synthesis of a peptide correspondlng to la was achieved according to the route D, and the peptrde obtained was ldentlcal with natural Toxin I In regard to TLC, W, MS

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