Synthetic transformation of santonin int
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Harapanhalli, Ravi S.
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Article
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1988
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John Wiley and Sons
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English
⚖ 383 KB
A seven-step synthesis of a new intermediate (5a,fa,llfi)-3,6dioxogermacr-l-cn-l3,7-olide (10) is describcd starting from [ -)-~-santonin (I). The key stcp in thc transformation was photolytic skclctal rearrangement of (4qSP,601,11 F)-S-hydroxy-2oxoeudesman-l3.6-olide (9) to the W e compound, scnsit