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Syntheses of 11-hydroxy and 11-hydroxy-11-methyl-14-methoxy-14-azadispiro[5.1.5.2]pentadec-9-ene-7,15-diones

✍ Scribed by Neelima; A. P. Bhaduri

Book ID
112127653
Publisher
Journal of Heterocyclic Chemistry
Year
1984
Tongue
English
Weight
131 KB
Volume
21
Category
Article
ISSN
0022-152X

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The preparation of a 11C-labelled 5-lipo
The preparation of a 11C-labelled 5-lipoxygenase product. 5(S)-hydroxy-6(R)-(N-[1-11C]acetyl)cysteinyl-7,9-trans-11,14-ciseicosatetraenoic acid
✍ Franz Oberdorfer; Thilo Siegel; Albrecht Guhlmann; Dietrich Keppler; Wolfgang Ma πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 French βš– 451 KB

## Abstract 5(S)‐Hydroxy‐6(R)‐(N‐[1‐^11^C]acetyl)cysteinyl‐7,9‐trans‐11,14‐cis‐eicosatetraenoic acid (N‐[1‐^11^C]acetyl leukotriene E~4~) was prepared by the reaction of leukotriene E~4~ and [1‐^11^C]acetyl chloride. The product was obtained with 1.3% yield, based on [1‐^11^C]acetyl chloride. The p