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Syntheses, antitumor activities, and antiangiogenesis of exo-3,6-epoxy-1,2,3,6-tetrahydrophthalimidoethanoyl- 5-fluorouracil and its polymers

โœ Scribed by Il-Doo Chung; Eun-Young Jung; Young-Woo Lee; Seon-Hee Kim; Chang-Sik Ha; Won-Jei Cho


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
177 KB
Volume
38
Category
Article
ISSN
0887-624X

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The new monomer, โฃ-methoxy-exo-3,6-epoxy-1,2,3,6-tetrahydrophthaloyl-5-fluorouracil (METFU), was synthesized by the reaction of 5-fluorouracil (5-FU) and exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride (ETA) in order to prepare polymers containing 5-FU moiety. Poly(โฃ-methoxy-exo-3,6-epoxy-1,2,3,6

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The new monomer, โฃ-ethoxy-exo-3,6-epoxy-1,2,3,6-tetrahydrophthaloyl-5fluorouracil (EETFU), was synthesized from 5-fluorouracil (5-FU) and โฃ-ethoxy-exo-3,6epoxy-1,2,3,6-tetrahydrophthaloyl chloride. Its homopolymer and copolymers with acrylic acid (AA) and vinyl acetate (VAc) were synthesized by phot

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The new monomer, 3,6-endo-methylene-1,2,3,6-tetrahydrophthalimidopropanoyl-5-fluorouracil (ETPFU), was synthesized by the reaction of 5-fluorouracil (5-FU) and 3,6-endo-methylene-1,2,3,6-tetrahydrophthalimidopropanoyl chloride (ETPC). The homopolymer of ETPFU and its copolymers with acrylic acid (AA

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