The cyclization of 4-aryl-1-arylsulfonylthiosemicarbazides 3, which were prepared by treatment of arylsulfonyl chlorides 1 with 4-aryl-3-thiosemicarbazides 2, with chloroacetyl chloride, provided the corresponding 2-arylamino-4-arylsulfonyl-4H-1,3,4-thiadiazin-5(6H)-ones 4 in good yields. The struct
โฆ LIBER โฆ
Syntheses and structural features of substituted 4,5,6,7-tetrahydroindazolin-3-ones
โ Scribed by G.H. Alt; J.P. Chupp
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- French
- Weight
- 172 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
received ir, UK fcr publication 3 July 1970) The literature abounds in pyrazoline chemistry, stemming in part from a search for effective medicinal compounds of the antipyrine type. Nevertheless there is a surprising exiguity in certain areas, such as the alkylation of 4,-5,6,7-tetrahydroindazolin-3-one (1). The differentiation between (2) and (II), and their properties, has been hampered by inadequate synthetic methods and by doubts regarding the authenticity of structural assignments.
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