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Syntheses and pharmacological activity of compounds related to the antidepressant, 5-(2-dimethylaminoethyl)-2,3-di-hydro-2-phenyl-1,5-benzothiazepin-4(5H)-one (thiazesim). III

✍ Scribed by Krapcho, John; Turk, Chester F.; Piala, Joseph J.


Book ID
126009142
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
503 KB
Volume
11
Category
Article
ISSN
0022-2623

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## Abstract The reaction of 2‐chloro‐4‐(methylsulfonyl)benzoyl chloride (5) with 1‐methyl‐1__H__‐2,1‐benzothiazin‐4‐(3__H__)‐one 2,2‐dioxide (4) gave the __O__‐benzoyl compound, 1‐methyl‐2,2‐dioxido‐1__H__‐2,1‐benzothiazin‐4‐yl 2‐chloro‐4‐(methylsulfonyl)benzoate (6), which rearranged to give the C