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Syntheses and conformational analyses of the perhydrofuro[2,3-b]furan compounds by using lanthanide shift reagent and empirical force-field calculation

✍ Scribed by Yasuhiro Kojima; Natsuki Kato; Yukimasa Terada


Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
274 KB
Volume
20
Category
Article
ISSN
0040-4039

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✦ Synopsis


Butyl-7-hydroxyperhydrofuro[2,3-blfuran was synthesized via a furan-alcohol which was derived by a coupling reaction with an epoxide and a new reagent, Li di(3-furyllcuprate. The configuration of the t-butyl substituent and the conformation of the furo[2,3-blfuran ring were decided by the combination of the LIS experiment and the empirical force-field calculation.