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Syntheses and activities of sulfur and selenium isosteric substitution analogs of retinol

✍ Scribed by Welch, Steven C.; Gruber, John M.


Book ID
126962531
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
392 KB
Volume
22
Category
Article
ISSN
0022-2623

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Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors and members of the nuclear hormone receptor superfamily. Herein, we describe an efficient synthesis of a novel isosteric selenium analog of the highly specific PPARbeta/delta ligand 2-methyl-4-((4-methyl-2