𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthese von fungicid wirksamen (1H-1,2,4-Triazol-1-yl-methyl)silanen und -siloxanen

✍ Scribed by Liebner, Falk ;Bankwitz, Uwe ;Rühlmann, Klaus

Book ID
102901944
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
609 KB
Volume
1994
Category
Article
ISSN
0947-3440

No coin nor oath required. For personal study only.

✦ Synopsis

Synthesis of Fungicidal (1__H__‐1,2,4‐Triazol‐1‐yl‐methyl)silanes and ‐siloxanes

The synthesis of Flusilazole^TM^ (1a) was substantially improved by thorough exclusion of oxygen nucleophiles in the reaction of (chloromethyl)bis(4‐fluorophenyl)methylsilane with sodium 1__H__‐1,2,4‐triazolide. New α,α‐diaryl‐α‐(1__H__‐1,2,4‐triazol‐1‐yl‐methyl)siloxanes 3 were obtained firstly from diaryl(1__H__‐1,2,4‐triazol‐1‐yl‐methyl)silanols or ‐silanolates, which were prepared by different methods from the corresponding silanol hydrochlorides and further treated with functional, linear oligodimethylsiloxanes or secondly from α,α‐diaryl‐α‐(chloromethyl)siloxanes and 1‐(trimethylsilyl)‐1__H__‐1,2,4‐triazole. The siloxane 4 containing a triazolylmethyl group and additionally silicofunctional coupling groups could be synthesized by hydrosilylation of an α‐triazolylmethyl‐ω‐vinylsiloxane with triethoxysilane. magnified image

📜 SIMILAR VOLUMES

4-Phenyl-3-[(1H-1,2,4-triazol-1-yl)­meth
4-Phenyl-3-[(1H-1,2,4-triazol-1-yl)­methyl]-1H-1,2,4-triazole-5-thione
✍ Jian, Fang-Fang ;Bai, Zheng-Shuai ;Li, Kai ;Xiao, Hai-Lian 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 359 KB

Single-crystal X-ray study T = 295 K Mean '(C±C) = 0.003 A Ê R factor = 0.034 wR factor = 0.084 Data-to-parameter ratio = 12.8 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

1-(4-Methyl­phen­yl)-3-(1H-1,2,4-triazol
1-(4-Methyl­phen­yl)-3-(1H-1,2,4-triazol-1-yl)propan-1-one
✍ Wan, Jun ;Li, Chun-Li ;Li, Xue-Mei ;Wang, Shi-Ying ;Zhang, Shu-Sheng 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 100 KB

In the title compound, C 12 H 13 N 3 O, the benzene and triazole rings make a dihedral angle of 59.6 (2) . The crystal packing is stabilized by weak C-HÁ Á Á interactions and van der Waals forces.