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Synthese von 2,2a,3,4-Tetrahydro-azeto[1,2-d]benz[b]-1,4-oxazin-2,4-dionen

✍ Scribed by Sabrina Schmaldienst; Karl-Hans Ongania


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
449 KB
Volume
316
Category
Article
ISSN
0365-6233

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✦ Synopsis


52a, A-6020 Innsbruck Eingegangen am 29. Marz 1982 Die 1-(2-Hydroxyary1)-4-oxo-azetidin-2-carbonsauren 7c, 7d und 10 cyclisieren mit Dicyclohexylcarbodiimid zu den Titelverbindungen 11, l2 und W. 13 ist auaerdem durch Nitrierung von 12 zuganglich. Die Zwischenstufen 7c, 7d und 10 werden uber die l-Aryl-4-oxo-azetidin-2,2-dicarbonsaureester 4a und 4bdargestellt aus 1 analog Sheehan') oder uber 8 und 9erhalten. Synthesis of 2,2a,3,4-Tetrahydroazeto[l,2-~benzo[b]e-2,4-diones The 1-(2-hydroxyaryl)-4-oxoazetidine-2-carboxylic acids 7e, 7d and 10 react with dicyclohexylcarbodiimide to give the title compounds 11,l2 and 13. Compound 13 can also be obtained by nitration of


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The mass spectrometric behaviour of nine 2a,4-disubstituted 2-chloro/2,2-dichloro-2,2a,3,4-tetrahydro-1Hazeto[2,1-d][1,5]benzothiazepin-1-ones has been studied with the aid of mass-analysed ion kinetic energy spectrometry and accurate mass measurements under electron impact ionization. All compounds