✦ LIBER ✦
Synthese von 2-substituierten und 2,3-disubstituierten Alkyl- und Aryl-thiophenen und 2,3-anellierten Thiophen-Derivaten aus Ketonen als C2-Bausteine und Carbonodithiosäure-O-ethyl-S-(2-oxoethyl)ester als C2S-Baustein
✍ Scribed by Erwin Aldvogel
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- German
- Weight
- 328 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Synthesis
of 2-Substituted and 2,3-Disubstituted Alkyl-und Aryl-thiophenes and Related 2,3-Anellated Thiophene Derivatives, Using Ketones and Carbonodithioic Acid 0-Ethyl S-(2-Oxoethyl) Ester as the Building Blocks
A simple method to synthesize 2-substituted and 2,3-disubstituted alkyl-and aryl-thiophenes as well as related 2,3-anellated thiophenes 6, starting from ketones 1 as C2-fragment and the S-protected carbonodithionic-acid derivative 3 as a C2S-fragment is described. The aldols 4 are intermediates of the two step process.