✦ LIBER ✦

Synthese und Konfiguration einiger Spiro [indan-2,2′-pyrrolidin]- und Spiro [pyrrolidin-2,2′-tetralin]-Derivate,

✍ Scribed by André P. Stoll; Trevor James Petcher; Hans Peter Weber

Book ID: 102251921
Publisher: John Wiley and Sons
Year: 1979
Tongue: German
Weight: 465 KB
Volume: 62
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19790620433

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✦ Synopsis

Synthesis and configuration of some spiro [indan‐2,2′‐pyrrolidine] and spiro [pyrrolidine‐2,2′‐tetraline] derivatives

Catalytic hydrogenation of the nitrosoindan and nitrosotetralin derivatives 8 yielded trans‐1‐hydroxy‐spiro [indan‐2,2′‐pyrrolidin]‐5′‐one (9) and trans‐1′‐hydroxy‐spiro [pyrrolidine‐2,2′‐tetralin]‐5‐one (10) respectively, whilst the corresponding cis compounds 12 and 15 were prepared via the chlorides 11 and 14.

The configurations of 10 and 13 were determined by X‐Ray analysis.

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