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Synthese der Cycloamide derxylo-3′-Amino-3′-desoxyadenosin-5′-phosphorsäure und −5′-thionophosphorsäure, zweier neuer cAMP-Analoga

✍ Scribed by Morr, Michael ;Mengel, Rudolf


Publisher
Wiley (John Wiley & Sons)
Year
1977
Tongue
English
Weight
167 KB
Volume
110
Category
Article
ISSN
0009-2940

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✦ Synopsis


Abstract

Synthesis of the Cycloamides of xylo‐3′‐Amino‐3′‐deoxyadenosine −5′‐phosphoric Acid and −5′‐thionophosphoric Acid, two New cAMP Analogues

xylo‐3′‐Amino‐3′‐deoxyadenosine (1) reacts with phosphoryl chloride or with thiophosphoryl chloride to yield the adenosine‐3′,5′‐cyclophosphates 3a or 3b, respectively, in high yields.