Synthese de vinylidene-3 pyrrolidines, piperidines, perhydroazepines a partir D'ω-monoalkyl-aminopropargyltrimethylsilanes par processus D'aminomethylation-desilylation intramoleculaire

✍ Scribed by D. Damour; J. Pornet; L. Miginiac

• Publisher: Elsevier Science
• Year: 1987
• Tongue: French
• Weight: 138 KB
• Volume: 28
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)96598-5

✦ Synopsis

In acidic medium, the cu-monoalkylaminopropargyltrimethylsilanes regiospecifically reacted with formaldehyde, affording 3-vinylidene nitrogen-containing heterocycles, such as 3-vinylidene pyrrolidines, piperidines and perhydroazepines.