Synphilin-1 inhibits alpha-synuclein degradation by the proteasome
✍ Scribed by Beatriz Alvarez-Castelao; José G. Castaño
- Book ID
- 105759417
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 595 KB
- Volume
- 68
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Normal mammary epithelial cells are rapidly induced to G~1~ arrest by the widely expressed cytokine, transforming growth factor beta (TGF‐β1). Studies in established breast cancer cell lines that express the estrogen receptor alpha (ERα) have demonstrated loss of this responsiveness. Th
Transforming growth factor beta1 (TGF beta 1)-induced G2 arrest was observed when a proliferation inhibitory function of the retinoblastoma protein (Rb) was compromised, but the mechanism underlying the G2 arrest was poorly characterized compared with that of G1 arrest. In the present study, we char