Synergy of DNA methylation and histone deacetylase inhibitors in the re-expression of RASSF1A and P16 genes silenced in QBC cells
β Scribed by Hong Li; Shaoqin Chen; Yi Shu; Yongjun Chen; Ying Su; Xin Wang; Shengquan Zou
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 151 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1610-1979
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## Abstract Loss of p16^INK4a^ protein expression has frequently been related to DNA methylation in association with gene silencing. Although the methylation status of exon1Ξ± for p16^INK4a^ involvement in various cancers has been extensively analyzed, it has been pointed out that some inconsistenci